Annual report pursuant to Section 13 and 15(d)

Shareholders' Deficit (Details Narrative)

v3.21.1
Shareholders' Deficit (Details Narrative) - USD ($)
12 Months Ended
Jun. 11, 2020
May 18, 2020
Jan. 29, 2020
Dec. 22, 2017
Feb. 07, 2017
Feb. 22, 2013
Dec. 31, 2020
Dec. 31, 2019
Nov. 11, 2019
Dec. 31, 2018
Number of shares authorized             1,000,000 1,000,000    
Preferred stock, par value             $ 0.001 $ 0.001    
Preferred stock, outstanding             25,000 25,000    
Stated value dividend             0.00% 0.00%    
Warrant term               2 years    
Loss on debt extinguishment             $ (555,430) $ 73,503 [1]    
Debt discount after amortization             $ 225,171 $ 2,044,940    
Common stock, shares authorized             2,500,000,000 2,500,000,000    
Issuance of common stock, value             $ 100,000 $ 168,343 [1]    
Common stock price per share             $ 0.0001 $ 0.0001    
Shares issued for conversion of notes payable and accrued interest             $ 3,339,109 $ 7,533,318 [1]    
Common stock issued for services             109,800 $ 159,850 [1]    
Common stock issued with exchange of convertible notes             58,855      
Stock issued value conversion of series C induced to convert                  
Stock issued value conversion of series C             $ 125      
Number of stock option exercisable shares             514,080      
Stock options exercise price per share             $ 1.46      
Weighted average remaining life of stock option             1 year 8 months 2 days      
Number of remaining option forfeited             85,753    
Share based compensation expenses             $ 57,400 $ 31,012    
Vesting period             29 months      
Unrecognized share-based compensation for outstanding grant             $ 198,060      
Weighted average grant date fair value of stock options             $ 0.08 $ 14.49    
Stock option to officers             3,000,000 5,280    
Independent Contractor [Member]                    
Stock options exercise price per share             $ 0.15      
Stock option vested             250,000      
Fair value of stock option             $ 245,900      
Chief Medical Officer [Member]                    
Stock options exercise price per share             $ 11.60      
Stock option vested             660      
Fair value of stock option             $ 76,532      
Weighted average remaining life of stock option             3 years 4 months 17 days      
Number of stock option vested and exercisable             1,980      
Number of remaining option forfeited             3,300      
Board of Director [Member]                    
Stock option to officers 74,668,000                  
Restricted Common Stock [Member] | One Investor [Member]                    
Common stock issued with exchange of convertible notes             $ 58,855      
Stock issued value conversion of series C induced to convert, shares             500,000      
Stock issued value conversion of series C induced to convert             $ 55,000      
Stock issued value conversion of series C, shares             55,000      
Variable Notes [Member]                    
Loss on debt extinguishment             $ 151,496      
Investment Agreement [Member]                    
Common stock issued with exchange cash, shares             0 17,900    
Common stock issued with exchange cash             $ 0 $ 168,343    
Equity Line Purchase Agreement [Member] | Cavalry Fund I LP [Member]                    
Purchase obligation   $ 10,000,000                
Commitment shares to be issued pro-rata   $ 3,000,000                
Commitment share description   The ELPA provides that at any time after the effective date of the registration statement and provided the closing sale price of the common shares on the OTCQB is not below $0.01, from time to time on any business day selected by the Company (the "Purchase Date"), the Company shall have the right, but not the obligation, to direct the investor to buy up to 300,000 shares of the common stock (the "regular purchase amount") at a purchase price equal to the lower of: (i) the lowest applicable sales price on the date of the put and (ii) 85% of the arithmetic average of the 3 lowest closing prices for the common stock during the 10 consecutive trading days ending on the trading day immediately preceding such put date. The regular purchase amount may be increased as follows: to up to 400,000 shares of common stock if the closing price of the common shares is not below $0.25 per share and up to 500,000 shares if the closing price is not below $0.40 per share.                
Proceeds of puts to the payment   50.00%                
Securities Purchase Agreement [Member]                    
Issuance of common stock, value             $ 100,000 $ 168,343    
Issuance of common stock             1,234,568 17,900    
Maximum [Member]                    
Number of warrant to purchase common stock               960    
Warrant exercise price               $ 27.90    
Maximum [Member] | Independent Contractor [Member]                    
Number of stock option exercisable shares             3,000,000      
Stock option term             2 years      
Maximum [Member] | Chief Medical Officer [Member]                    
Number of stock option exercisable shares             5,280      
Maximum [Member] | Equity Line Purchase Agreement [Member] | Cavalry Fund I LP [Member] | Tranche One [Member]                    
Issuance of common stock, value   $ 300,000                
Maximum [Member] | Equity Line Purchase Agreement [Member] | Cavalry Fund I LP [Member] | Tranche Two [Member]                    
Issuance of common stock, value   $ 400,000                
Common stock price per share   $ 0.25                
Maximum [Member] | Equity Line Purchase Agreement [Member] | Cavalry Fund I LP [Member] | Tranche Three [Member]                    
Issuance of common stock, value   $ 500,000                
Common stock price per share   $ 0.40                
Minimum [Member]                    
Warrant exercise price               $ 14.50    
Minimum [Member] | Equity Line Purchase Agreement [Member] | Cavalry Fund I LP [Member]                    
Common stock price per share   $ 0.01                
Series AA Preferred Stock [Member]                    
Number of shares authorized           1,000,000        
Preferred stock, par value           $ 0.001        
Preferred stock voting rights           Each holder of outstanding shares of Series AA Super Voting Preferred Stock shall be entitled to one hundred thousand (100,000) votes for each share of Series AA Super Voting Preferred Stock held on the record date for the determination of stockholders entitled to vote at each meeting of stockholders of the Company.        
Preferred stock, outstanding             25,000 25,000    
Series B Convertible Preferred Stock [Member]                    
Number of shares authorized         50,000          
Preferred stock, outstanding             600 600    
Stated value dividend         75.00%          
Warrant term         3 years          
Share exercise price, percentage         150.00%          
Liquidation value of preferred stock, per share         $ 100          
Series C Convertible Redeemable Preferred Stock [Member]                    
Number of shares authorized       8,000            
Liquidation value of preferred stock, per share             $ 1,000      
Preferred stock, dividend per share       $ 20.00            
Shares issued, price per share       $ 1,000            
Change in rights due to amended and restated certificate, description     The Company filed the amended and restated certificate of designation fort its Series C Secured Redeemable Preferred Stock. The amendment changed the rights of the Series C by (a) removing the requirement to redeem the Series C, (b) removing the obligation to pay dividends on the Series C, (c) Allowing the holders of shares of Series C to convert the stated value of their shares into common stock of the Company at 75% of the closing price of such common stock on the day prior to the conversion. The Series C preferred does not have any rights to vote with the common stock.              
Loss on debt extinguishment             $ 604,000      
Conversion of stock, shares converted             1,051      
Convertible preferred stock, shares outstanding             763 1,814    
Series C Preferred Stock [Member]                    
Sale of stock for preferred stock             0 94    
Sale of stock, consideration             $ 0 $ 94,000    
Debt discount after amortization             $ 0 $ 776    
Series C Preferred Stock [Member] | Maximum [Member]                    
Warrants issued to purchase common stock             0 960    
Common Stock [Member]                    
Conversion of stock, shares converted             2,754,822      
Obligated for resale amount                   $ 10,000,000
Common stock, shares authorized                   81,250
Average daily volume percentage                   200.00%
Issuance of common stock, value             $ 97,920 $ 26,545    
Issuance of common stock             771,926      
Shares issued for conversion of notes payable and accrued interest, shares             14,557,343 728,057    
Shares issued for conversion of notes payable and accrued interest             $ 3,339,109 $ 7,533,318    
Common stock issued for services, shares             1,206,398 10,340    
Common stock issued for services             $ 109,800 $ 159,850    
Common stock issued with exchange of convertible notes, shares             0 753    
Common stock issued with exchange of convertible notes             $ 0 $ 12,121    
Stock issued value conversion of series C induced to convert, shares             58,428      
Stock issued value conversion of series C induced to convert             $ 8,152      
Stock issued value conversion of series C, shares             2,754,822      
Stock issued value conversion of series C             $ 1,400,934      
Number of inducement on restricted shares, shares               355,000    
Number of inducement on restricted shares               $ 24,140    
Common Stock [Member] | Lock-Up Agreement [Member]                    
Common stock issued with exchange of convertible notes, shares             0 1,091    
Common stock issued with exchange of convertible notes             $ 0 $ 336,000    
Common Stock [Member] | Lock-Up Agreement [Member] | Two Promissory Notes [Member]                    
Common stock issued with exchange of convertible notes             $ 26,545      
Series D Convertible Preferred Stock [Member]                    
Number of shares authorized             20,000 20,000 20,000  
Preferred stock, par value             $ 0.0001 $ 0.0001    
Preferred stock, outstanding             305 255    
Liquidation value of preferred stock, per share             $ 1,000      
Convertible preferred stock, shares outstanding             305 255    
Conversion price percentage                 0.01%  
Convertible preferred stock, shares issued             305 255    
Preferred Stock Designated [Member]                    
Number of shares authorized             5,000,000      
Common Stock [Member]                    
Shares issued for Preferred Series D, shares                
Obligated for resale amount             $ 10,000,000      
Common stock, shares authorized             81,250      
Multiplied average price description             (i) 200% of the average daily volume (U.S. market only) of the common stock for the three (3) trading days prior to the date of delivery of the applicable put notice, multiplied by the average of the closing prices for such trading days or (ii) $100,000. The purchase price shall be set at ninety-four percent (94%) of the lowest daily VWAP of our common stock during the Pricing Period.      
Beneficial ownership percentage             4.99%      
Issuance of common stock, value             $ 123 $ 1 [1]    
Issuance of common stock             1,234,568 17,900 [1]    
Shares issued for conversion of notes payable and accrued interest, shares             14,557,343 728,057 [1]    
Shares issued for conversion of notes payable and accrued interest             $ 1,456 $ 73 [1]    
Common stock issued for services, shares             1,206,398 10,340 [1]    
Common stock issued for services             $ 120 $ 1 [1]    
Common stock issued with exchange of convertible notes, shares             409,000      
Common stock issued with exchange of convertible notes             $ 41      
Stock issued value conversion of series C induced to convert, shares             58,428      
Stock issued value conversion of series C induced to convert             $ 6      
Stock issued value conversion of series C, shares             2,754,822      
Stock issued value conversion of series C             $ 276      
Common Stock [Member] | Investment Agreement [Member]                    
Incurred fees             20,000      
Commitment Shares [Member] | Equity Line Purchase Agreement [Member] | Cavalry Fund I LP [Member] | Tranche One [Member]                    
Issuance of common stock, value   $ 500,000                
Commitment Shares [Member] | Equity Line Purchase Agreement [Member] | Cavalry Fund I LP [Member] | Tranche Two [Member]                    
Issuance of common stock, value   3,859,630                
Commitment Shares [Member] | Equity Line Purchase Agreement [Member] | Cavalry Fund I LP [Member] | Tranche Three [Member]                    
Issuance of common stock, value   $ 385,963                
Stock Options [Member]                    
Issuance of common stock, value             $ 165,000      
Issuance of common stock             1,500,000      
Stock issued for reverse stock splits             34,690      
[1] The consolidated financial statements have been retroactively restated to reflect the 1,000-for-1-reverse stock split that occurred on December 20, 2019.